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Target
Somatostatin receptor type 1
Ligand
BDBM50326854
Substrate
n/a
Meas. Tech.
ChEMBL_662922 (CHEMBL1252083)
IC50
>10000±n/a nM
Citation
 Abbenante, G; Becker, B; Blanc, S; Clark, C; Condie, G; Fraser, G; Grathwohl, M; Halliday, J; Henderson, S; Lam, A; Liu, L; Mann, M; Muldoon, C; Pearson, A; Premraj, R; Ramsdale, T; Rossetti, T; Schafer, K; Le Thanh, G; Tometzki, G; Vari, F; Verquin, G; Waanders, J; West, M; Wimmer, N; Yau, A; Zuegg, J; Meutermans, W Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold. J Med Chem 53:5576-86 (2010) [PubMed]  Article
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM50326854
Synonyms:
(Naphth-2-yl)methyl-2-(4'-Aminobutyrylamido)-3-O-(4'-chlorobenzyl)-2-deoxy-6-O-methyl-beta-D-glucopyranoside | CHEMBL1254235
Type:
Small organic molecule
Emp. Form.:
C29H35ClN2O6
Mol. Mass.:
543.051
SMILES:
COC[C@H]1O[C@@H](OCc2ccc3ccccc3c2)[C@H](NC(=O)CCCN)[C@@H](OCc2ccc(Cl)cc2)[C@@H]1O |r|
Structure:
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