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Target
D(1A) dopamine receptor
Ligand
BDBM50347560
Substrate
n/a
Meas. Tech.
ChEMBL_756891 (CHEMBL1803357)
Ki
380±n/a nM
Citation
 Reinart, R; Gyulai, Z; Berényi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A New 2-thioether-substituted apomorphines as potent and selective dopamine D2 receptor agonists. Eur J Med Chem 46:2992-9 (2011) [PubMed]  Article
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50347560
Synonyms:
CHEMBL1802235
Type:
Small organic molecule
Emp. Form.:
C21H24N2O4S
Mol. Mass.:
400.491
SMILES:
COC(=O)[C@@H](N)CSc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 |r|
Structure:
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