Reaction Details  Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50366037
Substrate
n/a
Meas. Tech.
ChEMBL_807332 (CHEMBL1960512)
Ki
5740±n/a nM
Citation
 Carta, F; Vullo, D; Maresca, A; Scozzafava, A; Supuran, CT New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II. Bioorg Med Chem Lett 22:2182-5 (2012) [PubMed]  Article
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50366037
Synonyms:
CHEMBL1955873
Type:
Small organic molecule
Emp. Form.:
C7H6OS
Mol. Mass.:
138.187
SMILES:
OC(=S)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: