Reaction Details  Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50454460
Substrate
n/a
Meas. Tech.
ChEMBL_30486 (CHEMBL641438)
Ki
7.4±n/a nM
Citation
 Baraldi, PG; Cacciari, B; Spalluto, G; Ji, XD; Olah, ME; Stiles, G; Dionisotti, S; Zocchi, C; Ongini, E; Jacobson, KA Novel N6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A3 adenosine receptors. J Med Chem 39:802-6 (1996) [PubMed]  Article
Target
Name:
Adenosine receptor A3
Synonyms:
AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3
Type:
PROTEIN
Mol. Mass.:
36643.73
Organism:
Rattus norvegicus
Description:
ChEMBL_479910
Residue:
320
Sequence:
MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
  
Inhibitor
Name:
BDBM50454460
Synonyms:
CHEMBL2113637
Type:
Small organic molecule
Emp. Form.:
C19H20ClN7O5
Mol. Mass.:
461.859
SMILES:
CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC(=O)Nc3ccccc3Cl)ncnc12 |r|
Structure:
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