Reaction Details  Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM50074846
Substrate
n/a
Meas. Tech.
ChEMBL_58342 (CHEMBL671957)
IC50
>1000±n/a nM
Citation
 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine sigma ligands as potential antipsychotic drugs. J Med Chem 42:1076-87 (1999) [PubMed]  Article
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50074846
Synonyms:
CHEMBL545597 | [3-(4-Methoxy-3-phenethyloxy-phenyl)-propyl]-dipropyl-amine; hydrochloride
Type:
Small organic molecule
Emp. Form.:
C24H35NO2
Mol. Mass.:
369.5402
SMILES:
CCCN(CCC)CCCc1ccc(OC)c(OCCc2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: