Reaction Details  Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50369515
Substrate
n/a
Meas. Tech.
ChEMBL_32008 (CHEMBL646605)
Ki
31±n/a nM
Citation
 van Tilburg, EW; von Frijtag Drabbe Künzel, J; de Groote, M; Vollinga, RC; Lorenzen, A; IJzerman, AP N6,5'-Disubstituted adenosine derivatives as partial agonists for the human adenosine A3 receptor. J Med Chem 42:1393-400 (1999) [PubMed]  Article
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50369515
Synonyms:
CHEMBL604636
Type:
Small organic molecule
Emp. Form.:
C20H19ClN6O5
Mol. Mass.:
458.855
SMILES:
COc1cccc(CNc2nc(Cl)nc3n(cnc23)C2O[C@@H]([C@H](O)[C@@H]2O)c2ccon2)c1 |r|
Structure:
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