Reaction Details  Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50097423
Substrate
n/a
Meas. Tech.
ChEMBL_29483 (CHEMBL641717)
Ki
32±n/a nM
Citation
 van Muijlwijk-Koezen, JE; Timmerman, H; Vollinga, RC; Frijtag von Drabbe Künzel, J; de Groote, M; Visser, S; IJzerman, AP Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists. J Med Chem 44:749-62 (2001) [PubMed]
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50097423
Synonyms:
4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide | 4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide(LUF5417) | 4-methoxy-N-(3-phenyl-1,2,4-thiadiazol-5-yl)benzamide | CHEMBL305322 | LUF-5417
Type:
Small organic molecule
Emp. Form.:
C16H13N3O2S
Mol. Mass.:
311.358
SMILES:
COc1ccc(cc1)C(=O)Nc1nc(ns1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: