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Target
5-hydroxytryptamine receptor 4
Ligand
BDBM50122872
Substrate
n/a
Meas. Tech.
ChEMBL_3373 (CHEMBL620610)
Ki
7.5±n/a nM
Citation
 Langlois, M; Fischmeister, R 5-HT4 receptor ligands: applications and new prospects. J Med Chem 46:319-44 (2003) [PubMed]
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4
Type:
Enzyme
Mol. Mass.:
43767.54
Organism:
Homo sapiens (Human)
Description:
Q13639
Residue:
388
Sequence:
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
  
Inhibitor
Name:
BDBM50122872
Synonyms:
4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide | CHEMBL117287 | PRUCALOPRIDE | US9663465, prucalopride
Type:
Small organic molecule
Emp. Form.:
C18H26ClN3O3
Mol. Mass.:
367.87
SMILES:
COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12
Structure:
Search PDB for entries with ligand similarity: