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Target
Serine/threonine-protein kinase pim-3
Ligand
BDBM50130248
Substrate
n/a
Meas. Tech.
ChEMBL_586743 (CHEMBL1062887)
IC50
880±n/a nM
Citation
 Bain, J; Plater, L; Elliott, M; Shpiro, N; Hastie, CJ; McLauchlan, H; Klevernic, I; Arthur, JS; Alessi, DR; Cohen, P The selectivity of protein kinase inhibitors: a further update. Biochem J 408:297-315 (2007) [PubMed]  Article
Target
Name:
Serine/threonine-protein kinase pim-3
Synonyms:
PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3)
Type:
Protein
Mol. Mass.:
35888.19
Organism:
Homo sapiens (Human)
Description:
Q86V86
Residue:
326
Sequence:
MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGVPESCDLRLCTLDPDDVASTTSSSESL
  
Inhibitor
Name:
BDBM50130248
Synonyms:
CHEMBL79004 | N-(6-Chloro-9H-beta-carbolin-8-yl)-nicotinamide | PS-1145
Type:
Small organic molecule
Emp. Form.:
C17H11ClN4O
Mol. Mass.:
322.748
SMILES:
Clc1cc(NC(=O)c2cccnc2)c2[nH]c3cnccc3c2c1
Structure:
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