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Target
Galanin receptor type 2
Ligand
BDBM50423646
Substrate
n/a
Meas. Tech.
ChEMBL_610353 (CHEMBL1072085)
Ki
34100±n/a nM
Citation
 Robertson, CR; Scholl, EA; Pruess, TH; Green, BR; White, HS; Bulaj, G Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery. J Med Chem 53:1871-5 (2010) [PubMed]  Article
Target
Name:
Galanin receptor type 2
Synonyms:
GALR2_RAT | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galnr2 | Galr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40697.04
Organism:
RAT
Description:
Galanin R2 GALR2 RAT::O08726
Residue:
372
Sequence:
MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPNCTASSRTLDPAC
  
Inhibitor
Name:
BDBM50423646
Synonyms:
CHEMBL2309599 | Galnon
Type:
Small organic molecule
Emp. Form.:
C40H46N4O6
Mol. Mass.:
678.8164
SMILES:
Cc1cc(=O)oc2cc(NC(=O)[C@@H](CCCCN)NC(=O)[C@H](CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc34)ccc12 |r|
Structure:
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