Reaction Details  Report a problem with these data
Target
Carbonic anhydrase 1
Ligand
BDBM13075
Substrate
n/a
Meas. Tech.
ChEMBL_612146 (CHEMBL1073568)
IC50
430±n/a nM
Citation
 Yenikaya, C; Sari, M; Bülbül, M; Ilkimen, H; Celik, H; Büyükgüngör, O Synthesis, characterization and antiglaucoma activity of a novel proton transfer compound and a mixed-ligand Zn(II) complex. Bioorg Med Chem 18:930-8 (2010) [PubMed]  Article
Target
Name:
Carbonic anhydrase 1
Synonyms:
CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:
Enzyme
Mol. Mass.:
28873.37
Organism:
Homo sapiens (Human)
Description:
P00915
Residue:
261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
  
Inhibitor
Name:
BDBM13075
Synonyms:
2,4-dichloro-5-sulfamoylbenzoic acid | 2000-01951 | Lasamide (Hsba) | LeadQuest Compound 9
Type:
Small organic molecule
Emp. Form.:
C7H5Cl2NO4S
Mol. Mass.:
270.09
SMILES:
NS(=O)(=O)c1cc(C(O)=O)c(Cl)cc1Cl
Structure:
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