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Target
Low molecular weight protein-tyrosine phosphatase A
Ligand
BDBM50284960
Substrate
n/a
Meas. Tech.
ChEMBL_639376 (CHEMBL1167756)
IC50
28000±n/a nM
Citation
 Mascarello, A; Chiaradia, LD; Vernal, J; Villarino, A; Guido, RV; Perizzolo, P; Poirier, V; Wong, D; Martins, PG; Nunes, RJ; Yunes, RA; Andricopulo, AD; Av-Gay, Y; Terenzi, H Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: kinetics, molecular modeling, toxicity and effect on growth. Bioorg Med Chem 18:3783-9 (2010) [PubMed]  Article
Target
Name:
Low molecular weight protein-tyrosine phosphatase A
Synonyms:
PTPA_MYCTU | PTPase | Probable low molecular weight protein-tyrosine-phosphatase | Protein Tyrosine Phosphatase PTPA | mptpA | ptpA
Type:
Hydrolase
Mol. Mass.:
17891.84
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
163
Sequence:
MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARNGPS
  
Inhibitor
Name:
BDBM50284960
Synonyms:
CHEMBL50626 | H3VO4 | Vanadiumsaeure | [VO(OH)3] | trihydrogen(tetraoxidovanadate)trihydroxidooxidovanadium | vanadic acid
Type:
Small organic molecule
Emp. Form.:
H3O4V
Mol. Mass.:
117.9629
SMILES:
O[V](O)(O)=O
Structure:
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