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Target
Carboxypeptidase B
Ligand
BDBM50395730
Substrate
n/a
Meas. Tech.
ChEMBL_860206 (CHEMBL2168946)
IC50
370000±n/a nM
Citation
 Yoshimoto, N; Sasaki, T; Sugimoto, K; Ishii, H; Yamamoto, K Design and characterization of a selenium-containing inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa), a zinc-containing metalloprotease. J Med Chem 55:7696-705 (2012) [PubMed]  Article
Target
Name:
Carboxypeptidase B
Synonyms:
CBPB1_PIG | CPB | CPB1
Type:
PROTEIN
Mol. Mass.:
47371.10
Organism:
Sus scrofa
Description:
ChEMBL_453905
Residue:
416
Sequence:
MLAFLILVTVTLASAHHSGEHFEGEKVFRVNVEDENDISLLHELASTRQIDFWKPDSVTQIKPHSTVDFRVKAEDILAVEDFLEQNELQYEVLINNLRSVLEAQFDSRVRTTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL
  
Inhibitor
Name:
BDBM50395730
Synonyms:
CHEMBL2164450
Type:
Small organic molecule
Emp. Form.:
C18H20Cl2N4O4Se2
Mol. Mass.:
585.2
SMILES:
Nc1ncc(CC(C[Se][Se]CC(Cc2cnc(N)c(Cl)c2)C(O)=O)C(O)=O)cc1Cl
Structure:
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