Reaction Details  Report a problem with these data
Target
5-hydroxytryptamine receptor 2B
Ligand
BDBM30701
Substrate
n/a
Meas. Tech.
ChEMBL_2918 (CHEMBL617633)
Kd
1071.52±n/a nM
Citation
 Glennon, RA; Jacyno, JM; Salley, JJ 2,3-dihydro and carbocyclic analogues of tryptamines: interaction with serotonin receptors. J Med Chem 25:68-70 (1982) [PubMed]
Target
Name:
5-hydroxytryptamine receptor 2B
Synonyms:
5-HT2B | 5-hydroxytryptamine receptor 2B | 5HT2B_RAT | Htr2b | Serotonin 2b (5-HT2b) receptor | Serotonin receptor 2a and 2b (5HT2A and 5HT2B) | Srl
Type:
Enzyme Catalytic Domain
Mol. Mass.:
53668.47
Organism:
RAT
Description:
5-HT2B HTR2B RAT::P30994
Residue:
479
Sequence:
MASSYKMSEQSTISEHILQKTCDHLILTDRSGLKAESAAEEMKQTAENQGNTVHWAALLIFAVIIPTIGGNILVILAVSLEKRLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEATWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRTTAFVKITVVWLISIGIAIPVPIKGIEADVVNAHNITCELTKDRFGSFMLFGSLAAFFAPLTIMIVTYFLTIHALRKKAYLVRNRPPQRLTRWTVSTVLQREDSSFSSPEKMVMLDGSHKDKILPNSTDETLMRRMSSAGKKPAQTISNEQRASKVLGIVFLFFLLMWCPFFITNVTLALCDSCNQTTLKTLLQIFVWVGYVSSGVNPLIYTLFNKTFREAFGRYITCNYQATKSVKVLRKCSSTLYFGNSMVENSKFFTKHGIRNGINPAMYQSPVRLRSSTIQSSSIILLNTFLTENDGDKVEDQVSYI
  
Inhibitor
Name:
BDBM30701
Synonyms:
2-(1H-indol-3-yl)-N-methyl-ethanamine | 2-(1H-indol-3-yl)-N-methylethanamine | 2-(1H-indol-3-yl)ethyl-methyl-amine | MLS000069493 | N-OMEGA-METHYLTRYPTAMINE | N-methyltryptamine | SMR000059062 | cid_6088
Type:
Small organic molecule
Emp. Form.:
C11H14N2
Mol. Mass.:
174.2423
SMILES:
CNCCc1c[nH]c2ccccc12
Structure:
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