Target

Ligand

Substrate

Meas. Tech.

ChEMBL_454278 (CHEMBL903462)

Citation

 Jin, J; Wang, Y; Wang, F; Kerns, JK; Vinader, VM; Hancock, AP; Lindon, MJ; Stevenson, GI; Morrow, DM; Rao, P; Nguyen, C; Barrett, VJ; Browning, C; Hartmann, G; Andrew, DP; Sarau, HM; Foley, JJ; Jurewicz, AJ; Fornwald, JA; Harker, AJ; Moore, ML; Rivero, RA; Belmonte, KE; Connor, HE Oxazolidinones as novel human CCR8 antagonists. Bioorg Med Chem Lett 17:1722-5 (2007) [PubMed]  Article

More Info.:

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Name:

C-C chemokine receptor type 8

Synonyms:

CCR8 | CCR8_HUMAN | CKRL1 | CMKBR8 | CMKBRL2

Type:

PROTEIN

Mol. Mass.:

40855.53

Organism:

Homo sapiens (Human)

Description:

ChEMBL_454278

Residue:

355

Sequence:

MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL

Blast this sequence in BindingDB or PDB

  
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Name:

BDBM50423259

Synonyms:

CHEMBL395211

Type:

Small organic molecule

Emp. Form.:

C25H25Cl2N3O3

Mol. Mass.:

486.39

SMILES:

COc1ccc2nccc(C3CN(C4CCN(Cc5ccc(Cl)c(Cl)c5)CC4)C(=O)O3)c2c1

Structure:

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