Reaction Details  Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50433707
Substrate
n/a
Meas. Tech.
ChEMBL_959585 (CHEMBL2382530)
EC50
77±n/a nM
Citation
 Lu, H; Fei, H; Yang, F; Zheng, S; Hu, Q; Zhang, L; Yuan, J; Feng, J; Sun, P; Dong, Q Discovery of novel orally bioavailable GPR40 agonists. Bioorg Med Chem Lett 23:2920-4 (2013) [PubMed]  Article
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1_RAT | Ffar1 | G-protein coupled receptor 40 | Gpr40
Type:
PROTEIN
Mol. Mass.:
31848.38
Organism:
Rattus norvegicus
Description:
ChEMBL_1511162
Residue:
300
Sequence:
MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLACSDLLLAITLPLKAVEALASGVWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPCYSWGVCVAIWALVLCHLGLALGLEAPRGWVDNTTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVHSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLEGSWRKLGLITGAWSVVLNPLVTGYLGTGPGQGTICVTRTPRGTIQK
  
Inhibitor
Name:
BDBM50433707
Synonyms:
CHEMBL2381282
Type:
Small organic molecule
Emp. Form.:
C18H15BrO5
Mol. Mass.:
391.213
SMILES:
OC(=O)C[C@@H]1COc2cc3O[C@@H](COc3cc12)c1cccc(Br)c1 |r|
Structure:
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