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Target
Indolethylamine N-methyltransferase
Ligand
BDBM50000302
Substrate
n/a
Meas. Tech.
ChEMBL_1333667 (CHEMBL3231053)
IC50
2000±n/a nM
Citation
 Rokach, J; Hamel, P; Hunter, NR; Reader, G; Rooney, CS; Anderson, PS; Cragoe, EJ; Mandel, LR Cyclic amidine inhibitors of indolamine N-methyltransferase. J Med Chem 22:237-47 (1979) [PubMed]
Target
Name:
Indolethylamine N-methyltransferase
Synonyms:
Amine N-methyltransferase | Aromatic alkylamine N-methyltransferase | Arylamine N-methyltransferase | INMT | INMT_RABIT | Indolamine N-methyltransferase | Thioether S-methyltransferase
Type:
PROTEIN
Mol. Mass.:
28949.17
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_108264
Residue:
263
Sequence:
MEGGFTGGDEYQKHFLPRDYLNTYYSFQSGPSPEAEMLKFNLECLHKTFGPGGLQGDTLIDIGSGPTIYQVLAACESFKDITLSDFTDRNREELAKWLKKEPGAYDWTPALKFACELEGNSGRWQEKAEKLRATVKRVLKCDANLSNPLTPVVLPPADCVLTLLAMECACCSLDAYRAALRNLASLLKPGGHLVTTVTLQLSSYMVGEREFSCVALEKEEVEQAVLDAGFDIEQLLYSPQSYSASTAPNRGVCFLVARKKPGS
  
Inhibitor
Name:
BDBM50000302
Synonyms:
CHEMBL3228385
Type:
Small organic molecule
Emp. Form.:
C5H11ClN2OS
Mol. Mass.:
182.672
SMILES:
O.Cl.CN1C=CCSC1=N |c:2|
Structure:
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