Reaction Details  Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50238959
Substrate
n/a
Meas. Tech.
ChEMBL_1352081 (CHEMBL3267346)
Ki
865±n/a nM
Citation
 de Lera Ruiz, M; Lim, YH; Zheng, J Adenosine A2A receptor as a drug discovery target. J Med Chem 57:3623-50 (2014) [PubMed]  Article
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50238959
Synonyms:
2-isopropyl-4-(thiazol-2-yl)thieno[3,2-d]pyrimidine | CHEMBL407307
Type:
Small organic molecule
Emp. Form.:
C12H11N3S2
Mol. Mass.:
261.366
SMILES:
CC(C)c1nc(-c2nccs2)c2sccc2n1
Structure:
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