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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50018957
Substrate
n/a
Meas. Tech.
ChEMBL_1365257 (CHEMBL3293222)
Ki
81±n/a nM
Citation
 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Functionally selective dopamine D2, D3 receptor partial agonists. J Med Chem 57:4861-75 (2014) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Homo sapiens (Human)
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM50018957
Synonyms:
CHEMBL3287406
Type:
Small organic molecule
Emp. Form.:
C22H23Cl2N5O
Mol. Mass.:
444.357
SMILES:
Clc1cccc(N2CCN(CCCCOc3ccn4nc(cc4c3)C#N)CC2)c1Cl
Structure:
Search PDB for entries with ligand similarity: