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Target
D(1A) dopamine receptor
Ligand
BDBM50018957
Substrate
n/a
Meas. Tech.
ChEMBL_1364908 (CHEMBL3295079)
Ki
3500±n/a nM
Citation
 Möller, D; Kling, RC; Skultety, M; Leuner, K; Hübner, H; Gmeiner, P Functionally selective dopamine D2, D3 receptor partial agonists. J Med Chem 57:4861-75 (2014) [PubMed]  Article
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50018957
Synonyms:
CHEMBL3287406
Type:
Small organic molecule
Emp. Form.:
C22H23Cl2N5O
Mol. Mass.:
444.357
SMILES:
Clc1cccc(N2CCN(CCCCOc3ccn4nc(cc4c3)C#N)CC2)c1Cl
Structure:
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