Reaction Details  Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50046752
Substrate
n/a
Meas. Tech.
ChEMBL_1452788 (CHEMBL3365130)
IC50
830±n/a nM
Citation
 Kamal, A; Srinivasa Reddy, T; Polepalli, S; Paidakula, S; Srinivasulu, V; Ganga Reddy, V; Jain, N; Shankaraiah, N Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors. Bioorg Med Chem Lett 24:3356-60 (2014) [PubMed]  Article
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50046752
Synonyms:
CHEMBL3309648
Type:
Small organic molecule
Emp. Form.:
C24H16FN3O3
Mol. Mass.:
413.4005
SMILES:
COc1ccc(F)c(c1)C1C2=C(COC2=O)Nc2c1c1cccnc1c1ncccc21 |t:11|
Structure:
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