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Target
Mu-type opioid receptor
Ligand
BDBM50116169
Substrate
n/a
Meas. Tech.
ChEMBL_1514814 (CHEMBL3615232)
Ki
75780±n/a nM
Citation
 Nieto, CT; Gonzalez-Nunez, V; Rodríguez, RE; Diez, D; Garrido, NM Design, synthesis, pharmacological evaluation and molecular dynamics ofß-amino acids morphan-derivatives as novel ligands for opioid receptors. Eur J Med Chem 101:150-62 (2015) [PubMed]  Article
Target
Name:
Mu-type opioid receptor
Synonyms:
Mu opioid receptor-like OR2 | oprm1 | or2
Type:
PROTEIN
Mol. Mass.:
43012.33
Organism:
Danio rerio
Description:
ChEMBL_109864
Residue:
382
Sequence:
MMENTGNISDLLYALSNPMVSNSSIFCRNFSNSSGLVNMNSSVCDRTPELDKSSTPVIVAIIITALYSIVCVMGLVGNVLVMYVIIRYTKMKTATNIYIFNLALADSLATSTLPFQSVNYLMGTWPFGDELCKIVMSIDYYNMFTSIFTLTTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMVMASTTSDLHSNGIIDCTLLFPHPSWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIFVIIKALVTIPNSLLQTITWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCVPSPSVLDLQNSTRSRNPQRDGQSSGHTVDRTNQQV
  
Inhibitor
Name:
BDBM50116169
Synonyms:
CHEMBL3612245
Type:
Small organic molecule
Emp. Form.:
C19H27ClN2O3
Mol. Mass.:
366.882
SMILES:
Cl.[H][C@]12CCC[C@]([H])([C@@H]1C(=O)OC)N(CC2)C(=O)[C@@H](N)Cc1ccccc1 |r,TLB:16:13:8:3.5.4|
Structure:
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