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Target
Melatonin receptor type 1B
Ligand
BDBM50144311
Substrate
n/a
Meas. Tech.
ChEMBL_1551498 (CHEMBL3762919)
Ki
226±n/a nM
Citation
 Landagaray, E; Ettaoussi, M; Duroux, R; Boutin, JA; Caignard, DH; Delagrange, P; Melnyk, P; Berthelot, P; Yous, S Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives. Eur J Med Chem 109:360-70 (2016) [PubMed]  Article
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50144311
Synonyms:
CHEMBL3760044
Type:
Small organic molecule
Emp. Form.:
C18H20N2O3
Mol. Mass.:
312.363
SMILES:
CCNC(=O)NCCc1coc2ccc3ccc(OC)cc3c12
Structure:
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