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Target
D(3) dopamine receptor
Ligand
BDBM25392
Substrate
n/a
Meas. Tech.
ChEMBL_1573523 (CHEMBL3801478)
Ki
4700±n/a nM
Citation
 Weichert, D; Stanek, M; Hübner, H; Gmeiner, P Structure-guided development of dualß2 adrenergic/dopamine D2 receptor agonists. Bioorg Med Chem 24:2641-53 (2016) [PubMed]  Article
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM25392
Synonyms:
4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride | 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol | 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2 | CHEMBL434 | ISOPROTERONOL | Isoprenaline | Isoproterenol | Isoproterenol (-) | Isoproterenol,(+) | Isoproterenol-l | Norisodrine | Novodrin
Type:
Small organic molecule
Emp. Form.:
C11H17NO3
Mol. Mass.:
211.2576
SMILES:
CC(C)NCC(O)c1ccc(O)c(O)c1
Structure:
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