Reaction Details  Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50306384
Substrate
n/a
Meas. Tech.
ChEMBL_1585168 (CHEMBL3820976)
Ki
69±n/a nM
Citation
 Christiansen, E; Hudson, BD; Hansen, AH; Milligan, G; Ulven, T Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer. J Med Chem 59:4849-58 (2016) [PubMed]  Article
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50306384
Synonyms:
5-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yloxy)-2-methylbenzyl)thiazolidine-2,4-dione | CHEMBL604126
Type:
Small organic molecule
Emp. Form.:
C17H12ClF3N2O3S
Mol. Mass.:
416.802
SMILES:
Cc1cc(Oc2ncc(cc2Cl)C(F)(F)F)ccc1Cc1sc(=O)[nH]c1O
Structure:
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