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Target
Glutamate receptor
Ligand
BDBM17660
Substrate
n/a
Ki
16.46±n/a nM
Comments
PDSP_3724
Citation
 Toms, NJ; Reid, ME; Phillips, W; Kemp, MC; Roberts, PJ A novel kainate receptor ligand [3H]-(2S,4R)-4-methylglutamate: pharmacological characterization in rabbit brain membranes. Neuropharmacology 36:1483-8 (1997) [PubMed]  Article
Target
Name:
Glutamate receptor
Synonyms:
Glutamate kainate | Glutamate-Kainate
Type:
Enzyme Catalytic Domain
Mol. Mass.:
96238.98
Organism:
RABBIT
Description:
Glutamate-Kainate Glutamate kainate RABBIT::G1SXH9
Residue:
849
Sequence:
MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEAQWDGLTGRITFNKTDGLRKNFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTEGNKDRSNNITDSLANRTLIVTTILEEPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDVEQCLSFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA
  
Inhibitor
Name:
BDBM17660
Synonyms:
(2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid | 2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid | CHEMBL279956 | Quisqualate | Quisqualate, L | quisqualic acid
Type:
Small organic molecule
Emp. Form.:
C5H7N3O5
Mol. Mass.:
189.1262
SMILES:
N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O
Structure:
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