Reaction Details  Report a problem with these data
Target
Carbonic anhydrase 5A, mitochondrial
Ligand
BDBM85658
Substrate
n/a
Meas. Tech.
CA Assay
pH
7.4±0
Temperature
293.15±0 K
Ki
47±0.0 nM
Citation
 Supuran, CT; Scozzafava, A Benzolamide is not a membrane-impermeant carbonic anhydrase inhibitor. J Enzyme Inhib Med Chem 19:269-73 (2004) [PubMed]  Article
Target
Name:
Carbonic anhydrase 5A, mitochondrial
Synonyms:
CAH5A_MOUSE | Ca5 | Ca5a | Car5 | Car5a | Carbonate dehydratase VA | Carbonic Anhydrase V | Carbonic Anhydrase VA | Carbonic anhydrase 5A, mitochondrial precursor
Type:
Enzyme
Mol. Mass.:
34081.17
Organism:
Mus musculus (mouse)
Description:
Full length murine, cloned isozyme.
Residue:
299
Sequence:
MLRRDPRKPLAILRHVGLLCATGPQRWRFQHSCAEEHSNCARHPLWTGPVSSAEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGYFFQVEFDDSCEDSGISGGPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLAVIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGPFDPSCLLPACRDYWTYPGSLTTPPLAESVTWIVQKTPVEVSPSQLSTFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFRLDRTKMRS
  
Inhibitor
Name:
BDBM85658
Synonyms:
EZA4
Type:
Small organic molecule
Emp. Form.:
C10H10N2O3S
Mol. Mass.:
238.263
SMILES:
CCOc1ccc2nc(sc2c1)C(=O)ON
Structure:
Search PDB for entries with ligand similarity: