Reaction Details  Report a problem with these data
Target
Norepinephrine transporter
Ligand
BDBM86058
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_3044
Citation
 Chaki, S; Hirota, S; Funakoshi, T; Suzuki, Y; Suetake, S; Okubo, T; Ishii, T; Nakazato, A; Okuyama, S Anxiolytic-like and antidepressant-like activities of MCL0129 (1-[(S)-2-(4-fluorophenyl)-2-(4-isopropylpiperadin-1-yl)ethyl]-4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazine), a novel and potent nonpeptide antagonist of the melanocortin-4 receptor. J Pharmacol Exp Ther 304:818-26 (2003) [PubMed]  Article
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
  
Inhibitor
Name:
BDBM86058
Synonyms:
MCL0129
Type:
Small organic molecule
Emp. Form.:
C34H47FN4O
Mol. Mass.:
546.7616
SMILES:
COc1ccc2ccccc2c1CCCCN1CCN(C[C@@H](N2CCN(CC2)C(C)C)c2ccc(F)cc2)CC1
Structure:
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