Reaction Details  Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM29692
Substrate
n/a
IC50
7724±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID]
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM29692
Synonyms:
(2Z)-3-ethyl-2-[(E)-3-(3-ethyl-4,5-dihydro-1,3-thiazol-3-ium-2-yl)prop-2-enylidene]-1,3-thiazolidine;iodide | (2Z)-3-ethyl-2-[(E)-3-(3-ethyl-4,5-dihydrothiazol-3-ium-2-yl)prop-2-enylidene]thiazolidine;iodide | 3-ethyl-2-[(E,3E)-3-(3-ethylthiazolidin-2-ylidene)prop-1-enyl]-2-thiazolin-3-ium;iodide | 3-ethyl-2-[(E,3Z)-3-(3-ethylthiazolidin-2-ylidene)prop-1-enyl]-2-thiazolin-3-ium;iodide | MLS000764534 | SMR000290139 | cid_6504365
Type:
Small organic molecule
Emp. Form.:
C13H21N2S2
Mol. Mass.:
269.449
SMILES:
CCN1CCS\C1=C/C=C/C1=[N+](CC)CCS1 |c:11|
Structure:
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