Reaction Details  Report a problem with these data
Target
Glutathione S-transferase P
Ligand
BDBM233186
Substrate
n/a
Meas. Tech.
GST Assay
IC50
>1.00e+5±n/a nM
Citation
 Mangoyi, R; Hayeshi, R; Ngadjui, B; Ngandeu, F; Bezabih, M; Abegaz, B; Razafimahefa, S; Rasoanaivo, P; Mukanganyama, S Glutathione transferase from Plasmodium falciparum--interaction with malagashanine and selected plant natural products. J Enzyme Inhib Med Chem 25:854-62 (2010) [PubMed]  Article
Target
Name:
Glutathione S-transferase P
Synonyms:
FAEES3 | GST class-pi | GST3 | GSTP1 | GSTP1-1 | GSTP1_HUMAN | Glutathione S-transferase | Glutathione S-transferase (GST) | Glutathione S-transferase P | Glutathione S-transferase Pi | Glutathione transferase (GST)
Type:
Enzyme
Mol. Mass.:
23353.53
Organism:
Homo sapiens (Human)
Description:
P09211
Residue:
210
Sequence:
MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
  
Inhibitor
Name:
BDBM233186
Synonyms:
Malagashanine
Type:
Small organic molecule
Emp. Form.:
C23H30N2O4
Mol. Mass.:
398.4953
SMILES:
COC(=O)[C@H]1[C@@H](C)OC[C@H]2[C@@H]3N(C(C)=O)c4ccccc4[C@@]33CCN(C)[C@@H]3C[C@@H]12 |r|
Structure:
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