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Target
Tyrosine-protein phosphatase non-receptor type 1 [1-321]
Ligand
BDBM604159
Substrate
n/a
Meas. Tech.
Metabolic Measurements
Ki
9000±n/a nM
Citation
 Tonks, N; Krishnan, N Treatment of Rett syndrome US Patent  US11660306 Publication Date 5/30/2023
Target
Name:
Tyrosine-protein phosphatase non-receptor type 1 [1-321]
Synonyms:
PTN1_HUMAN | PTP1B | PTPN1 | Protein tyrosine phosphatase 1B (PTP1B)
Type:
Enzyme
Mol. Mass.:
37311.71
Organism:
Homo sapiens (Human)
Description:
P18031 (1-321 aa)
Residue:
321
Sequence:
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHN
  
Inhibitor
Name:
BDBM604159
Synonyms:
US11660306, Example hopane
Type:
Small organic molecule
Emp. Form.:
C30H52
Mol. Mass.:
412.7339
SMILES:
CC(C)[C@H]1CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2CC[C@@H]2[C@@]3(C)CCCC(C)(C)[C@@H]3CC[C@@]12C |r|
Structure:
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