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Target
Heme oxygenase 1
Ligand
BDBM651665
Substrate
n/a
Meas. Tech.
ELISA Assay to Measure Human Heme Oxygenase-1 (HMOX-1) in HepG2 lysate
EC50
800±n/a nM
Citation
 Biddle, M; Kluge, A; Sasmal, S; Lagu, B; Wu, X; Ogiyama, T; Bell, E HMOX1 INDUCERS US Patent  US20240051952 Publication Date 2/15/2024
Target
Name:
Heme oxygenase 1
Synonyms:
HMOX1 | HMOX1_HUMAN | HO | HO-1 | HO1
Type:
PROTEIN
Mol. Mass.:
32822.24
Organism:
Homo sapiens (Human)
Description:
ChEMBL_368941
Residue:
288
Sequence:
MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM
  
Inhibitor
Name:
BDBM651665
Synonyms:
2-(benzo[d]oxazol-2-yl- amino)-N-(2-methoxy- ethyl)-1-methyl-1H- benzo[d]imidazole-5- carboxamide | US20240051952, Example 1i
Type:
Small organic molecule
Emp. Form.:
C19H19N5O3
Mol. Mass.:
365.3859
SMILES:
COCCNC(=O)c1ccc2n(C)c(Nc3nc4ccccc4o3)nc2c1
Structure:
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