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Target
Heme oxygenase 1
Ligand
BDBM651706
Substrate
n/a
Meas. Tech.
ELISA Assay to Measure Human Heme Oxygenase-1 (HMOX-1) in HepG2 lysate
EC50
2000±n/a nM
Citation
 Biddle, M; Kluge, A; Sasmal, S; Lagu, B; Wu, X; Ogiyama, T; Bell, E HMOX1 INDUCERS US Patent  US20240051952 Publication Date 2/15/2024
Target
Name:
Heme oxygenase 1
Synonyms:
HMOX1 | HMOX1_HUMAN | HO | HO-1 | HO1
Type:
PROTEIN
Mol. Mass.:
32822.24
Organism:
Homo sapiens (Human)
Description:
ChEMBL_368941
Residue:
288
Sequence:
MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM
  
Inhibitor
Name:
BDBM651706
Synonyms:
N-(1,3-dihydroxy- propan-2-yl)-1-methyl- 2-((6-(trifluorometh- oxy)benzo[d]oxazol-2- yl)amino)-1H-benzo- [d]imidazole-5-carbox- amide | US20240051952, Example 48
Type:
Small organic molecule
Emp. Form.:
C20H18F3N5O5
Mol. Mass.:
465.3826
SMILES:
Cn1c(Nc2nc3ccc(OC(F)(F)F)cc3o2)nc2cc(ccc12)C(=O)NC(CO)CO
Structure:
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