Reaction Details  Report a problem with these data
Target
60S ribosomal protein L19-A
Ligand
BDBM65998
Substrate
n/a
Meas. Tech.
Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits
EC50
9714±n/a nM
Citation
 PubChem, PC Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically RPL19A based on MLPCN hits PubChem Bioassay (2010)[AID]
Target
Name:
60S ribosomal protein L19-A
Synonyms:
RL19A_YEAST | RPL19A | RPL23A | YL14A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21739.62
Organism:
Saccharomyces cerevisiae
Description:
gi_536029
Residue:
189
Sequence:
MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
  
Inhibitor
Name:
BDBM65998
Synonyms:
5-nitro-2-thiophenecarboxylic acid [2-(4-tert-butylanilino)-2-oxoethyl] ester | 5-nitrothiophene-2-carboxylic acid [2-(4-tert-butylanilino)-2-keto-ethyl] ester | MLS000374776 | SMR000254130 | [2-(4-tert-butylanilino)-2-oxoethyl] 5-nitrothiophene-2-carboxylate | [2-[(4-tert-butylphenyl)amino]-2-oxidanylidene-ethyl] 5-nitrothiophene-2-carboxylate | cid_2411698
Type:
Small organic molecule
Emp. Form.:
C17H18N2O5S
Mol. Mass.:
362.4
SMILES:
CC(C)(C)c1ccc(NC(=O)COC(=O)c2ccc(s2)[N+]([O-])=O)cc1
Structure:
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