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Target
Sentrin-specific protease 8
Ligand
BDBM84018
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
9690±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID]
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84018
Synonyms:
3-(3-pyridyl)-5-[(E)-styryl]-1,2,4-oxadiazole | 5-[(E)-2-phenylethenyl]-3-(3-pyridinyl)-1,2,4-oxadiazole | 5-[(E)-2-phenylethenyl]-3-pyridin-3-yl-1,2,4-oxadiazole | MLS-0280140.0002 | cid_5348455
Type:
Small organic molecule
Emp. Form.:
C15H11N3O
Mol. Mass.:
249.2673
SMILES:
C(=C/c1ccccc1)\c1nc(no1)-c1cccnc1
Structure:
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