Reaction Details  Report a problem with these data
Target
Sentrin-specific protease 8
Ligand
BDBM84043
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
619±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID]
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84043
Synonyms:
MLS-0454431.0001 | N-(6-chloranyl-1,3-benzothiazol-2-yl)-1-methyl-pyrrole-2-carboxamide | N-(6-chloro-1,3-benzothiazol-2-yl)-1-methyl-2-pyrrolecarboxamide | N-(6-chloro-1,3-benzothiazol-2-yl)-1-methyl-pyrrole-2-carboxamide | N-(6-chloro-1,3-benzothiazol-2-yl)-1-methylpyrrole-2-carboxamide | cid_49852540
Type:
Small organic molecule
Emp. Form.:
C13H10ClN3OS
Mol. Mass.:
291.756
SMILES:
Cn1cccc1C(=O)Nc1nc2ccc(Cl)cc2s1
Structure:
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