Reaction Details  Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50420166
Substrate
n/a
Meas. Tech.
ChEMBL_1746748 (CHEMBL4181258)
EC50
127±n/a nM
Citation
 Li, Z; Xu, X; Li, G; Fu, X; Liu, Y; Feng, Y; Wang, M; Ouyang, Y; Han, J Improving metabolic stability with deuterium: The discovery of GPU-028, a potent free fatty acid receptor 4 agonists. Bioorg Med Chem 25:6647-6652 (2017) [PubMed]  Article
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50420166
Synonyms:
CHEMBL2058532
Type:
Small organic molecule
Emp. Form.:
C22H19FO3
Mol. Mass.:
350.3829
SMILES:
OC(=O)CCc1ccc(OCc2cc(F)ccc2-c2ccccc2)cc1
Structure:
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