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Target
Chitooligosaccharidolytic beta-N-acetylglucosaminidase
Ligand
BDBM50452812
Substrate
n/a
Meas. Tech.
ChEMBL_1748392 (CHEMBL4182902)
Ki
21810±n/a nM
Citation
 Chen, W; Shen, S; Dong, L; Zhang, J; Yang, Q Selective inhibition of ?-N-acetylhexosaminidases by thioglycosyl-naphthalimide hybrid molecules. Bioorg Med Chem 26:394-400 (2018) [PubMed]  Article
Target
Name:
Chitooligosaccharidolytic beta-N-acetylglucosaminidase
Synonyms:
3.2.1.52 | Beta-hexosaminidase
Type:
PROTEIN
Mol. Mass.:
67953.88
Organism:
Ostrinia furnacalis
Description:
ChEMBL_117835
Residue:
594
Sequence:
MWSRRIPLFIFGVLVLILSVAAEDVVWRWSCDNGKCVKLKNDPRSSEPALSLEACKMFCNEYGLLWPRPTGEADLGNFLSKINLNSIEVKILKKGATDDLMEAAAKRFKEQVSLAIPRGSTPKLTGKAVDVYLVNENPNEKAFSLEMDESYGLRVSPSGADRVNATITANSFFGMRHGLETLSQLFVFDDIRDHLLMVRDVNISDKPVYPYRGILLDTARNYYSIESIKRTIEAMAAVKLNTFHWHITDSQSFPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTDLTVCFKAEPWKSYCVEPPCGQLNPTKDELYQYLEDIYSDMAEVFDTTDIFHMGGDEVSEACWNSSDSIQNFMMQNRWDLDKESFLKLWNYFQQKAQDKAYKAFGKKLPLILWTSTLTNYKHIDDYLNKDDYIIQVWTTGVDPQIKGLLEKGYRLIMSNYDALYFDCGYGAWVGAGNNWCSPYIGWQKVYDNSPAVIALEHRDQVLGGEAALWSEQSDTSTLDGRLWPRAAALAERLWAEPATSWQDAEYRMLHIRERLVRMGIQAESLQPEWCYQNEGYCYS
  
Inhibitor
Name:
BDBM50452812
Synonyms:
CHEMBL4216247
Type:
Small organic molecule
Emp. Form.:
C29H35N5O7S
Mol. Mass.:
597.682
SMILES:
CC(=O)N[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)SCCCCCCn1cc(CN2C(=O)c3cccc4cccc(C2=O)c34)nn1 |r|
Structure:
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