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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50053906
Substrate
n/a
Meas. Tech.
ChEMBL_157546 (CHEMBL764930)
Ki
0.175±n/a nM
Citation
 Romines, KR; Morris, JK; Howe, WJ; Tomich, PK; Horng, MM; Chong, KT; Hinshaw, RR; Anderson, DJ; Strohbach, JW; Turner, SR; Mizsak, SA Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationships. J Med Chem 39:4125-30 (1996) [PubMed]  Article
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50053906
Synonyms:
4-Cyano-N-{3-[1-(4-hydroxy-2-oxo-4a,5,6,7,8,9,10,10a-octahydro-2H-cycloocta[b]pyran-3-yl)-propyl]-phenyl}-benzenesulfonamide | CHEMBL133804
Type:
Small organic molecule
Emp. Form.:
C27H30N2O5S
Mol. Mass.:
494.603
SMILES:
CCC(C1C(=O)OC2CCCCCCC2C1=O)c1cccc(NS(=O)(=O)c2ccc(cc2)C#N)c1
Structure:
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