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Target
Fatty acid-binding protein, heart
Ligand
BDBM50538229
Substrate
n/a
Meas. Tech.
ChEMBL_1972440 (CHEMBL4605258)
Ki
1000±n/a nM
Citation
 Su, H; Zou, Y; Chen, G; Dou, H; Xie, H; Yuan, X; Zhang, X; Zhang, N; Li, M; Xu, Y Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J Med Chem 63:4090-4106 (2020) [PubMed]  Article
Target
Name:
Fatty acid-binding protein, heart
Synonyms:
FABP11 | FABP3 | FABPH_HUMAN | Fatty acid binding protein muscle | MDGI
Type:
PROTEIN
Mol. Mass.:
14858.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463784
Residue:
133
Sequence:
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
  
Inhibitor
Name:
BDBM50538229
Synonyms:
CHEMBL4632412
Type:
Small organic molecule
Emp. Form.:
C19H14ClNO2
Mol. Mass.:
323.773
SMILES:
OC(=O)c1ccccc1Nc1cccc(Cl)c1-c1ccccc1
Structure:
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