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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50545402
Substrate
n/a
Meas. Tech.
ChEMBL_1995014 (CHEMBL4628909)
EC50
>10000±n/a nM
Citation
 Dorich, S; Cox, JH; Burch, JD; Chagnon, F; Chen, B; Léger, S; St-Onge, M; Fader, LD Novel pyridone EP Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM50545402
Synonyms:
CHEMBL4640391
Type:
Small organic molecule
Emp. Form.:
C22H25Cl2NO4
Mol. Mass.:
438.344
SMILES:
CCCCCC(O)\C=C\c1c(Cl)cc(Cl)c(=O)n1CCc1ccc(cc1)C(O)=O
Structure:
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