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Target
Galectin-8
Ligand
BDBM50230648
Substrate
n/a
Meas. Tech.
ChEMBL_2016288 (CHEMBL4669866)
Kd
2300±n/a nM
Citation
 Patel, B; Kishor, C; Houston, TA; Shatz-Azoulay, H; Zick, Y; Vinik, Y; Blanchard, H Rational Design and Synthesis of Methyl-?-d-galactomalonyl Phenyl Esters as Potent Galectin-8 J Med Chem 63:11573-11584 (2020) [PubMed]  Article
Target
Name:
Galectin-8
Synonyms:
Gal-8 | LEG8_HUMAN | LGALS8 | PCTA-1 | Po66 carbohydrate-binding protein | Po66-CBP | Prostate carcinoma tumor antigen 1
Type:
PROTEIN
Mol. Mass.:
35814.23
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1454625
Residue:
317
Sequence:
MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
  
Inhibitor
Name:
BDBM50230648
Synonyms:
CHEMBL3764379
Type:
Small organic molecule
Emp. Form.:
C23H39NO19
Mol. Mass.:
633.5511
SMILES:
[H][C@@]1(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)O[C@H](CO)[C@H](O)[C@H](O[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@]([H])(O2)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]1O |r|
Structure:
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