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Target
Galectin-8
Ligand
BDBM50572248
Substrate
n/a
Meas. Tech.
ChEMBL_2116637 (CHEMBL4825578)
Kd
48000±n/a nM
Citation
 Hassan, M; Baussière, F; Guzelj, S; Sundin, AP; Håkansson, M; Kova?i?, R; Leffler, H; Toma?i?, T; Anderluh, M; Jakopin, ?; Nilsson, UJ Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain. ACS Med Chem Lett 12:1745-1752 (2021) [PubMed]  Article
Target
Name:
Galectin-8
Synonyms:
Gal-8 | LEG8_HUMAN | LGALS8 | PCTA-1 | Po66 carbohydrate-binding protein | Po66-CBP | Prostate carcinoma tumor antigen 1
Type:
PROTEIN
Mol. Mass.:
35814.23
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1454625
Residue:
317
Sequence:
MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
  
Inhibitor
Name:
BDBM50572248
Synonyms:
CHEMBL4850222
Type:
Small organic molecule
Emp. Form.:
C16H18N2O6
Mol. Mass.:
334.3239
SMILES:
Cn1c(CO[C@@H]2C=CO[C@H](CO)[C@@H]2O)nc2ccc(cc12)C(O)=O |r,c:6|
Structure:
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