Reaction Details  Report a problem with these data
Target
Arginase-1
Ligand
BDBM50561034
Substrate
n/a
Meas. Tech.
ChEMBL_2281205
IC50
5000±n/a nM
Citation
 Zhang, J; Zhang, Y; Qu, B; Yang, H; Hu, S; Dong, X If small molecules immunotherapy comes, can the prime be far behind? Eur J Med Chem 218:0 (2021) [PubMed]
Target
Name:
Arginase-1
Synonyms:
ARGI1_RAT | Arg1 | Liver-type arginase | Type I arginase
Type:
PROTEIN
Mol. Mass.:
34976.26
Organism:
Rattus norvegicus
Description:
ChEMBL_108287
Residue:
323
Sequence:
MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYLKPPK
  
Inhibitor
Name:
BDBM50561034
Synonyms:
CHEMBL4244287
Type:
Small organic molecule
Emp. Form.:
C5H12BNO4S
Mol. Mass.:
193.029
SMILES:
N[C@@H](CSCCB(O)O)C(O)=O |r|
Structure:
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