Reaction Details  Report a problem with these data
Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50610721
Substrate
n/a
Meas. Tech.
ChEMBL_2281774
IC50
18400±n/a nM
Citation
 Alizadeh, SR; Ebrahimzadeh, MA Pyrazolotriazines: Biological activities, synthetic strategies and recent developments. Eur J Med Chem 223:0 (2021) [PubMed]
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50610721
Synonyms:
CHEMBL5271736
Type:
Small organic molecule
Emp. Form.:
C17H13FN6
Mol. Mass.:
320.3237
SMILES:
Nc1nc(Nc2ccc(F)cc2)n2nc(cc2n1)-c1ccccc1
Structure:
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