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Target
Serine/threonine-protein kinase Nek7
Ligand
BDBM50355496
Substrate
n/a
Meas. Tech.
ChEMBL_2292043
Kd
210±n/a nM
Citation
 Wells, CI; Kapadia, NR; Couņago, RM; Drewry, DH In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the Nek family of kinases. Medchemcomm 9:44-66 (2018) [PubMed]
Target
Name:
Serine/threonine-protein kinase Nek7
Synonyms:
NEK kinase | NEK7 | NEK7_HUMAN
Type:
PROTEIN
Mol. Mass.:
34559.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_586832
Residue:
302
Sequence:
MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS
  
Inhibitor
Name:
BDBM50355496
Synonyms:
CHEMBL1908397
Type:
Small organic molecule
Emp. Form.:
C20H20N4O
Mol. Mass.:
332.399
SMILES:
O=C(N1CCNCC1)c1ccc(\C=C\c2n[nH]c3ccccc23)cc1
Structure:
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