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Target
Prostaglandin E2 receptor EP2 subtype
Ligand
BDBM50293510
Substrate
n/a
Meas. Tech.
ChEMBL_570543 (CHEMBL1026915)
IC50
654±n/a nM
Citation
 Cameron, KO; Lefker, BA; Ke, HZ; Li, M; Zawistoski, MP; Tjoa, CM; Wright, AS; DeNinno, SL; Paralkar, VM; Owen, TA; Yu, L; Thompson, DD Discovery of CP-533536: an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. Bioorg Med Chem Lett 19:2075-8 (2009) [PubMed]  Article
Target
Name:
Prostaglandin E2 receptor EP2 subtype
Synonyms:
PE2R2_RAT | Prostanoid EP2 receptor | Ptger2
Type:
PROTEIN
Mol. Mass.:
39786.37
Organism:
Rattus norvegicus
Description:
ChEMBL_1501400
Residue:
357
Sequence:
MDNSFNDSRRVENCESRQYLLSDESPAISSVMFTAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESRACTYFAFTMTFFSLATMLMLFAMALERYLAIGHPYFYRRRVSRRGGLAVLPAIYGVSLLFCSLPLLNYGEYVQYCPGTWCFIQHGRTAYLQLYATVLLLLIVAVLGCNISVILNLIRMQLRSKRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAVCSLPFTIFAYMDETSSRKEKWDLRALRFLSVNSIIDPWVFVILRPPVLRLMRSVLCCRTSLRAPEAPGASCSTQQTDLCGQL
  
Inhibitor
Name:
BDBM50293510
Synonyms:
4-(4-(N-(4-butylbenzyl)methylsulfonamido)phenyl)butanoic acid | CHEMBL559820
Type:
Small organic molecule
Emp. Form.:
C22H29NO4S
Mol. Mass.:
403.535
SMILES:
CCCCc1ccc(CN(c2ccc(CCCC(O)=O)cc2)S(C)(=O)=O)cc1
Structure:
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