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Target
Glucoamylase, intracellular sporulation-specific
Ligand
BDBM50371133
Substrate
n/a
Meas. Tech.
ChEMBL_444129 (CHEMBL893288)
IC50
150000±n/a nM
Citation
 Chevrier, C; Defoin, A; Tarnus, C Synthesis and evaluation of amino-threoses in D- and L-series: are five membered ring amino-sugars more potent glycosidase inhibitors than the six membered ones? Bioorg Med Chem 15:4125-35 (2007) [PubMed]  Article
Target
Name:
Glucoamylase, intracellular sporulation-specific
Synonyms:
1,4-alpha-D-glucan glucohydrolase | AMYG_YEAST | Glucan 1,4-alpha-glucosidase | SGA | SGA1
Type:
PROTEIN
Mol. Mass.:
61445.06
Organism:
Saccharomyces cerevisiae S288c
Description:
ChEMBL_444129
Residue:
549
Sequence:
MARQKMFYNKLLGMLSVGFGFAWALENITIYEFDFGKGILDQSYGGVFSNNGPSQVQLRDAVLMNGTVVYDSNGAWDSSALEEWLQGQKKVSIEKIFENIGPSAVYPSISPGVVIASPSQTHPDYFYQWIRDSALTINSIVSHSAGPAIETLLQYLNVSFHLQRSNNTLGAGIGYTNDTVALGDPKWNVDNTAFTEDWGRPQNDGPALRSIAILKIIDYIKQSGTDLGAKYPFQSTADIFDDIVRWDLRFIIDHWNSSGFDLWEEVNGMHFFTLLVQLSAVDKSLSYFNASERSSPFVEELRQTRRDISKFLVDPANGFINGKYNYIVGTPMIADTLRSGLDISTLLAANTVHDAPSASHLPFDINDPAVLNTLHHLMLHMRSIYPINDSSKNATGIALGRYPEDVYDGYGFGEGNPWVLATCTASTTLYQLIYRHISEQHDLVVPMNNDCSNAFWSELVFSNLTTLGNDEGYLILEFNTPAFNQTIQKIFQLADSFLVKLKAHVGTDGELSEQFNKYTGFMQGAQHLTWSYTSFWDAYQIRQEVLQSL
  
Inhibitor
Name:
BDBM50371133
Synonyms:
CHEMBL389969
Type:
Small organic molecule
Emp. Form.:
C4H7NO2
Mol. Mass.:
101.1039
SMILES:
O[C@H]1CNCC1=O
Structure:
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