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Target
Vitamin K epoxide reductase complex subunit 1
Ligand
BDBM50386851
Substrate
n/a
Meas. Tech.
ChEMBL_827366 (CHEMBL2051036)
Ki
79600±n/a nM
Citation
 Mladenovic, M; Mihailovic, M; Bogojevic, D; Vukovic, N; Sukdolak, S; Matic, S; Niciforovic, N; Mihailovic, V; Maškovic, P; Vrvic, MM; Solujic, S Biochemical and pharmacological evaluation of 4-hydroxychromen-2-ones bearing polar C-3 substituents as anticoagulants. Eur J Med Chem 54:144-58 (2012) [PubMed]  Article
Target
Name:
Vitamin K epoxide reductase complex subunit 1
Synonyms:
VKOR | VKOR1_HUMAN | VKORC1 | Vitamin K epoxide reductase complex subunit 1 | Vitamin K epoxide reductase complex subunit 1 (hVKORC1) | Vitamin K1 2,3-epoxide reductase subunit 1 | Vitamin k epoxide reductase complex subunit 1 isoform 1
Type:
Enzyme
Mol. Mass.:
18244.90
Organism:
Homo sapiens (Human)
Description:
Q9BQB6
Residue:
163
Sequence:
MGSTWGSPGWVRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYLAWILFFVLYDFCIVCITTYAINVSLMWLSFRKVQEPQGKAKRH
  
Inhibitor
Name:
BDBM50386851
Synonyms:
CHEMBL2048096
Type:
Small organic molecule
Emp. Form.:
C18H11N3O5S
Mol. Mass.:
381.362
SMILES:
Oc1c(-c2csc(Nc3cccc(c3)[N+]([O-])=O)n2)c(=O)oc2ccccc12
Structure:
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