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Target
Cysteine synthase
Ligand
BDBM50423701
Substrate
n/a
Meas. Tech.
ChEMBL_596272 (CHEMBL1050688)
Kd
2290868±n/a nM
Citation
 Salsi, E; Bayden, AS; Spyrakis, F; Amadasi, A; Campanini, B; Bettati, S; Dodatko, T; Cozzini, P; Kellogg, GE; Cook, PF; Roderick, SL; Mozzarelli, A Design of O-acetylserine sulfhydrylase inhibitors by mimicking nature. J Med Chem 53:345-56 (2010) [PubMed]  Article
Target
Name:
Cysteine synthase
Synonyms:
CSase | CYSK_HAEIN | O-acetylserine (thiol)-lyase | OAS-TL | cysK
Type:
PROTEIN
Mol. Mass.:
33385.00
Organism:
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Description:
ChEMBL_596272
Residue:
316
Sequence:
MAIYADNSYSIGNTPLVRLKHFGHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLTKGKEIVDATSGNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAKGMKGAIAKAEEIVASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLDLSIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSASERYLSTALFEGIEG
  
Inhibitor
Name:
BDBM50423701
Synonyms:
CHEMBL576268
Type:
Small organic molecule
Emp. Form.:
C22H38N6O9S
Mol. Mass.:
562.637
SMILES:
CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCSC)C(O)=O |r|
Structure:
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